Potassium buffering in the central nervous system
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چکیده
منابع مشابه
Otassium Buffering in the Central Nervous System
bstract —Rapid changes in extracellular K concentration [K ]o) in the mammalian CNS are counteracted by simple assive diffusion as well as by cellular mechanisms of K learance. Buffering of [K ]o can occur via glial or neuronal ptake of K ions through transporters or K -selective chanels. The best studied mechanism for [K ]o buffering in the rain is called K spatial buffering, wherein the glial...
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A one-dimensional numerical model of potassium dynamics in the central nervous system is developed. The model incorporates the following physiological processes in computing spatial and temporal changes in extracellular K+ concentration, [K+]o: 1) the release of K+ from K+ sources into extracellular space, 2) diffusion of K+ through extracellular space, 3) active uptake of K+ into cells and blo...
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ژورنال
عنوان ژورنال: Neuroscience
سال: 2004
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2004.06.008